Spyre Therapeutics, Inc.

SYRE stock score: 51/100

$91.40 · +7.88% · Scored Oct 20, 2026

Technical
65
Fundamental
37
News
53

The reading

Spyre Therapeutics (SYRE) scores 51 out of 100, which reads neutral, higher than 66% of Healthcare stocks and 45% of the 4,166 US stocks we score.

The composite is technicals and fundamentals weighted equally: technicals read 65, fundamentals 37.

Among the fundamentals, Quick Ratio at 100 and Price Target at 100 score highest, while Earnings Profitability (Quarterly) at 0 weighs the most against it.

On the daily chart, trend-following indicators average 62 and contrarian oscillators 51.

News sentiment is neutral at 53; it is shown, not counted in the composite.

Since Jul 25, 2026 the composite has ranged from 46 to 73, and it is down 22 points over the period.

What’s driving the score

The strongest and weakest of the scorers that count toward SYRE’s composite. Each returns 0–100, higher is more bullish — including metrics where low is good, like P/E.

Fundamental

37

Pulling it up

  • Quick Ratio100

    Quick ratio measures a company's ability to meet short-term obligations with liquid assets.

  • Price Target100

    Price target score compares the current stock price to analyst consensus targets.

  • Current Ratio100

    Current ratio measures ability to pay short-term liabilities with current assets.

Holding it back

  • Earnings Profitability (Quarterly)0

    Earnings Profitability (Quarterly) measures recent profitability using trailing 12-month quarterly data.

  • Earnings Quality (Annual)0

    Earnings Quality (Annual) assesses absolute profitability independent of growth, measuring whether the company is profitable, its earnings yield (earnings/market cap), profit margins, and consistency.

  • Earnings Growth (5-Year)0

    5-year earnings growth evaluates long-term profit trajectory and consistency.

32 weighted scorers; 9 had no data today and are left out rather than counted as zero.

Technical · daily

60

Pulling it up

  • VWAP100

    Volume Weighted Average Price (VWAP) shows the average price weighted by volume.

  • EMA 50 Cross Up100

    EMA 50 Cross Up detects when price crosses above the 50-period EMA.

  • SMA 20 Cross Up100

    SMA 20 Cross Up tracks when very short-term averages cross above the 20-period SMA.

Holding it back

  • TRIX13

    TRIX is a momentum oscillator that filters out short-term noise by triple-smoothing price data.

  • Bollinger Bands (20)15

    Bollinger Bands (20-period) plot standard deviations above and below a moving average.

  • Stock Volatility19

    Stock volatility measures price fluctuation magnitude over time.

62 weighted scorers; 3 had no data today and are left out rather than counted as zero.

News · shown, not counted

Global News
53

Technical score by timeframe

ChartScoreWeight
Hourly611
Daily603
Weekly652
Monthly662
Quarterly752

Composite score, last 90 days

05010051Jul 25, 2026Oct 20, 2026Jul 25, 2026: 73Jul 26, 2026: 73Jul 27, 2026: 59Jul 28, 2026: 59Jul 29, 2026: 58Jul 30, 2026: 58Jul 31, 2026: 58Aug 2, 2026: 54Aug 3, 2026: 53Aug 5, 2026: 56Aug 6, 2026: 57Aug 7, 2026: 56Aug 8, 2026: 57Aug 9, 2026: 57Aug 10, 2026: 57Aug 11, 2026: 55Aug 12, 2026: 56Aug 13, 2026: 56Aug 14, 2026: 55Aug 15, 2026: 56Aug 16, 2026: 56Aug 17, 2026: 57Aug 18, 2026: 57Aug 19, 2026: 57Aug 20, 2026: 56Aug 22, 2026: 52Aug 23, 2026: 52Aug 24, 2026: 53Aug 25, 2026: 51Aug 26, 2026: 48Aug 27, 2026: 48Aug 28, 2026: 48Aug 29, 2026: 48Aug 30, 2026: 48Aug 31, 2026: 47Sep 1, 2026: 49Sep 2, 2026: 47Sep 3, 2026: 48Sep 4, 2026: 49Sep 5, 2026: 49Sep 6, 2026: 49Sep 7, 2026: 49Sep 8, 2026: 50Sep 9, 2026: 48Sep 10, 2026: 48Sep 11, 2026: 50Sep 12, 2026: 49Sep 13, 2026: 49Sep 14, 2026: 50Sep 15, 2026: 48Sep 16, 2026: 49Sep 17, 2026: 50Sep 18, 2026: 48Sep 19, 2026: 49Sep 20, 2026: 49Sep 21, 2026: 50Sep 22, 2026: 50Sep 23, 2026: 49Sep 24, 2026: 48Sep 25, 2026: 47Sep 26, 2026: 47Sep 27, 2026: 47Sep 28, 2026: 47Sep 29, 2026: 47Sep 30, 2026: 50Oct 1, 2026: 51Oct 2, 2026: 52Oct 3, 2026: 52Oct 4, 2026: 52Oct 5, 2026: 50Oct 6, 2026: 46Oct 7, 2026: 46Oct 8, 2026: 46Oct 9, 2026: 48Oct 10, 2026: 48Oct 11, 2026: 48Oct 12, 2026: 49Oct 13, 2026: 46Oct 14, 2026: 46Oct 15, 2026: 46Oct 16, 2026: 47Oct 17, 2026: 46Oct 18, 2026: 46Oct 19, 2026: 48Oct 20, 2026: 51
Show the daily numbers
DateComposite
Oct 20, 202651
Oct 19, 202648
Oct 18, 202646
Oct 17, 202646
Oct 16, 202647
Oct 15, 202646
Oct 14, 202646
Oct 13, 202646
Oct 12, 202649
Oct 11, 202648
Oct 10, 202648
Oct 9, 202648
Oct 8, 202646
Oct 7, 202646
Oct 6, 202646
Oct 5, 202650
Oct 4, 202652
Oct 3, 202652
Oct 2, 202652
Oct 1, 202651
Sep 30, 202650
Sep 29, 202647
Sep 28, 202647
Sep 27, 202647
Sep 26, 202647
Sep 25, 202647
Sep 24, 202648
Sep 23, 202649
Sep 22, 202650
Sep 21, 202650
Sep 20, 202649
Sep 19, 202649
Sep 18, 202648
Sep 17, 202650
Sep 16, 202649
Sep 15, 202648
Sep 14, 202650
Sep 13, 202649
Sep 12, 202649
Sep 11, 202650
Sep 10, 202648
Sep 9, 202648
Sep 8, 202650
Sep 7, 202649
Sep 6, 202649
Sep 5, 202649
Sep 4, 202649
Sep 3, 202648
Sep 2, 202647
Sep 1, 202649
Aug 31, 202647
Aug 30, 202648
Aug 29, 202648
Aug 28, 202648
Aug 27, 202648
Aug 26, 202648
Aug 25, 202651
Aug 24, 202653
Aug 23, 202652
Aug 22, 202652
Aug 20, 202656
Aug 19, 202657
Aug 18, 202657
Aug 17, 202657
Aug 16, 202656
Aug 15, 202656
Aug 14, 202655
Aug 13, 202656
Aug 12, 202656
Aug 11, 202655
Aug 10, 202657
Aug 9, 202657
Aug 8, 202657
Aug 7, 202656
Aug 6, 202657
Aug 5, 202656
Aug 3, 202653
Aug 2, 202654
Jul 31, 202658
Jul 30, 202658
Jul 29, 202658
Jul 28, 202659
Jul 27, 202659
Jul 26, 202673
Jul 25, 202673

Key facts

Market cap
$8.5B
Sector
Healthcare
Industry
Biotechnology
Beta
3.11
Risk grade (1–10)
9
Next earnings
Nov 3, 2026

Biotechnology peers

CompanyMarket capScore
PTGX Protagonist Therapeutics$8.9B56
CYTK Cytokinetics$8.9B46
CAI Caris Life Sciences$8.8B58
AXSM Axsome Therapeutics$8.4B43
TGTX TG Therapeutics$8.3B67
ARWR Arrowhead Pharmaceuticals$8.3B47

Questions

What is SYRE's stock score today?

SYRE scores 51/100 (Neutral) as of Oct 20, 2026: technical 65, fundamental 37, and news sentiment 53, which is shown but not counted. Scores are recomputed every night.

Is SYRE a buy?

The score is not a buy or sell recommendation. A 51 says the technical and fundamental signals we measure lean neutral today, relative to every other stock scored the same way. Use the breakdown above to see why, and treat it as a starting point for your own research.

How is the SYRE score calculated?

94 weighted scorers feed it today: 32 fundamental, scored against Healthcare ranges, and 62 technical on the daily chart, with 5 timeframes blended into the technical total. Every scorer returns 0–100; missing data is left out, never counted as zero.

Scores are information, not investment advice. Computed from Yahoo Finance, Finnhub and Alpha Vantage data; technical indicators via TA-Lib. Past scores do not predict future returns.