Ionis Pharmaceuticals, Inc.

IONS stock score: 33/100

$42.93 · -2.23% · Scored Oct 23, 2026

Technical
35
Fundamental
31
News
58

The reading

Ionis Pharmaceuticals (IONS) scores 33 out of 100, which reads bearish, higher than 10% of Healthcare stocks and 5% of the 4,161 US stocks we score.

The composite is technicals and fundamentals weighted equally: technicals read 35, fundamentals 31.

Among the fundamentals, Quick Ratio at 100 and Price Target at 100 score highest, while Earnings Profitability (Quarterly) at 0 weighs the most against it.

On the daily chart, trend-following indicators average 25 and contrarian oscillators 56 — a split worth reading before trusting the technical total.

News sentiment is neutral at 58; it is shown, not counted in the composite.

Since Jul 25, 2026 the composite has ranged from 31 to 64, and it is down 25 points over the period.

What’s driving the score

The strongest and weakest of the scorers that count toward IONS’s composite. Each returns 0–100, higher is more bullish — including metrics where low is good, like P/E.

Fundamental

31

Pulling it up

  • Quick Ratio100

    Quick ratio measures a company's ability to meet short-term obligations with liquid assets.

  • Price Target100

    Price target score compares the current stock price to analyst consensus targets.

  • Current Ratio100

    Current ratio measures ability to pay short-term liabilities with current assets.

Holding it back

  • Earnings Profitability (Quarterly)0

    Earnings Profitability (Quarterly) measures recent profitability using trailing 12-month quarterly data.

  • Earnings Growth (Quarterly)0

    Quarterly earnings growth measures profit increase versus the prior-year quarter.

  • Earnings Quality (Annual)0

    Earnings Quality (Annual) assesses absolute profitability independent of growth, measuring whether the company is profitable, its earnings yield (earnings/market cap), profit margins, and consistency.

39 weighted scorers; 2 had no data today and are left out rather than counted as zero.

Technical · daily

27

Pulling it up

  • Parabolic SAR (PSAR)100

    Parabolic SAR (Stop and Reverse) provides trailing stop levels that follow price trends.

  • Candlestick Patterns100

    Candlestick patterns recognize specific price formations that historically suggest continuation or reversal.

  • Williams %R (28)77

    Williams %R (28-period) places the close within the last 28 periods' high-low range.

Holding it back

  • S&P 500 52W Comparison0

    S&P 500 52-week comparison evaluates the stock's annual performance relative to the broader market.

  • 52-Week Range0

    Where the price sits between its 52-week low and high.

  • SMA 2000

    Simple Moving Average (200-period) is the most widely followed long-term trend indicator.

62 weighted scorers; 3 had no data today and are left out rather than counted as zero.

News · shown, not counted

Global News
58

Technical score by timeframe

ChartScoreWeight
Hourly441
Daily273
Weekly252
Monthly422
Quarterly442

Composite score, last 90 days

05010033Jul 25, 2026Oct 23, 2026Jul 25, 2026: 58Jul 26, 2026: 58Jul 27, 2026: 60Jul 28, 2026: 59Jul 29, 2026: 64Jul 30, 2026: 63Jul 31, 2026: 63Aug 2, 2026: 48Aug 3, 2026: 49Aug 5, 2026: 48Aug 6, 2026: 48Aug 7, 2026: 45Aug 8, 2026: 45Aug 9, 2026: 45Aug 10, 2026: 45Aug 11, 2026: 44Aug 12, 2026: 45Aug 13, 2026: 44Aug 14, 2026: 44Aug 15, 2026: 44Aug 16, 2026: 44Aug 17, 2026: 46Aug 18, 2026: 46Aug 19, 2026: 48Aug 20, 2026: 45Aug 22, 2026: 43Aug 23, 2026: 43Aug 24, 2026: 44Aug 25, 2026: 45Aug 26, 2026: 45Aug 27, 2026: 44Aug 28, 2026: 43Aug 29, 2026: 42Aug 30, 2026: 42Aug 31, 2026: 42Sep 1, 2026: 42Sep 2, 2026: 41Sep 3, 2026: 39Sep 4, 2026: 37Sep 5, 2026: 37Sep 6, 2026: 37Sep 7, 2026: 37Sep 8, 2026: 39Sep 9, 2026: 38Sep 10, 2026: 38Sep 11, 2026: 37Sep 12, 2026: 37Sep 13, 2026: 37Sep 14, 2026: 36Sep 15, 2026: 33Sep 16, 2026: 31Sep 17, 2026: 33Sep 18, 2026: 32Sep 19, 2026: 32Sep 20, 2026: 32Sep 21, 2026: 32Sep 22, 2026: 34Sep 23, 2026: 33Sep 24, 2026: 33Sep 25, 2026: 33Sep 26, 2026: 33Sep 27, 2026: 33Sep 28, 2026: 34Sep 29, 2026: 34Sep 30, 2026: 33Oct 1, 2026: 32Oct 2, 2026: 33Oct 3, 2026: 33Oct 4, 2026: 33Oct 5, 2026: 33Oct 6, 2026: 34Oct 7, 2026: 34Oct 8, 2026: 33Oct 9, 2026: 35Oct 10, 2026: 34Oct 11, 2026: 34Oct 12, 2026: 33Oct 13, 2026: 32Oct 14, 2026: 32Oct 15, 2026: 34Oct 16, 2026: 33Oct 17, 2026: 33Oct 18, 2026: 33Oct 19, 2026: 34Oct 20, 2026: 35Oct 21, 2026: 36Oct 22, 2026: 34Oct 23, 2026: 33
Show the daily numbers
DateComposite
Oct 23, 202633
Oct 22, 202634
Oct 21, 202636
Oct 20, 202635
Oct 19, 202634
Oct 18, 202633
Oct 17, 202633
Oct 16, 202633
Oct 15, 202634
Oct 14, 202632
Oct 13, 202632
Oct 12, 202633
Oct 11, 202634
Oct 10, 202634
Oct 9, 202635
Oct 8, 202633
Oct 7, 202634
Oct 6, 202634
Oct 5, 202633
Oct 4, 202633
Oct 3, 202633
Oct 2, 202633
Oct 1, 202632
Sep 30, 202633
Sep 29, 202634
Sep 28, 202634
Sep 27, 202633
Sep 26, 202633
Sep 25, 202633
Sep 24, 202633
Sep 23, 202633
Sep 22, 202634
Sep 21, 202632
Sep 20, 202632
Sep 19, 202632
Sep 18, 202632
Sep 17, 202633
Sep 16, 202631
Sep 15, 202633
Sep 14, 202636
Sep 13, 202637
Sep 12, 202637
Sep 11, 202637
Sep 10, 202638
Sep 9, 202638
Sep 8, 202639
Sep 7, 202637
Sep 6, 202637
Sep 5, 202637
Sep 4, 202637
Sep 3, 202639
Sep 2, 202641
Sep 1, 202642
Aug 31, 202642
Aug 30, 202642
Aug 29, 202642
Aug 28, 202643
Aug 27, 202644
Aug 26, 202645
Aug 25, 202645
Aug 24, 202644
Aug 23, 202643
Aug 22, 202643
Aug 20, 202645
Aug 19, 202648
Aug 18, 202646
Aug 17, 202646
Aug 16, 202644
Aug 15, 202644
Aug 14, 202644
Aug 13, 202644
Aug 12, 202645
Aug 11, 202644
Aug 10, 202645
Aug 9, 202645
Aug 8, 202645
Aug 7, 202645
Aug 6, 202648
Aug 5, 202648
Aug 3, 202649
Aug 2, 202648
Jul 31, 202663
Jul 30, 202663
Jul 29, 202664
Jul 28, 202659
Jul 27, 202660
Jul 26, 202658
Jul 25, 202658

Key facts

Market cap
$7.1B
Sector
Healthcare
Industry
Biotechnology
Beta
0.38
Risk grade (1–10)
3
Next earnings
Nov 4, 2026

Biotechnology peers

CompanyMarket capScore
ARWR Arrowhead Pharmaceuticals$8.2B47
AXSM Axsome Therapeutics$8.2B43
TGTX TG Therapeutics$8.1B66
ABVX ABIVAX Société Anonyme$7.9B37
PRAX Praxis Precision Medicines$7.2B45
IOVA Iovance Biotherapeutics$6.4B52

Questions

What is IONS's stock score today?

IONS scores 33/100 (Bearish) as of Oct 23, 2026: technical 35, fundamental 31, and news sentiment 58, which is shown but not counted. Scores are recomputed every night.

Is IONS a buy?

The score is not a buy or sell recommendation. A 33 says the technical and fundamental signals we measure lean bearish today, relative to every other stock scored the same way. Use the breakdown above to see why, and treat it as a starting point for your own research.

How is the IONS score calculated?

101 weighted scorers feed it today: 39 fundamental, scored against Healthcare ranges, and 62 technical on the daily chart, with 5 timeframes blended into the technical total. Every scorer returns 0–100; missing data is left out, never counted as zero.

Scores are information, not investment advice. Computed from Yahoo Finance, Finnhub and Alpha Vantage data; technical indicators via TA-Lib. Past scores do not predict future returns.